PolyCAT A™ is a weak cation-exchange material (WCX) primarily used for protein variants involving deamidation, PEGylation, position of attachment, desialylation, etc., hemoglobin variant analysis, proteins with pI above 6.0, monoclonal antibodies
and histones. more...

PolyHYDROXYETHYL A™ This neutral, polar material was developed specifically for Hydrophilic Interaction Chromatography (HILIC). It's uses include analysis of polar small molecules for metabolomics or analysis via HILIC-MS/MS of specific small molecules, peptide separations and mapping involving differences in polar groups, multidimensional purification of synthetic and natural peptides or fractionation of really complex digests, HPLC of solutes that aren't soluble in aqueous media (membrane proteins;phospholipids), eliminating detergents, lipids, and salts from a sample, and oligonucleotides with their analogs.

In the absence of organic solvent, PolyHYDROXYETHYL A™ functions in the Size Exclusion Chromatography (SEC) mode. more...

PolySULFOETHYL A™ is a strong cation-exchange (SCX) material developed specifically for HPLC of peptides, it is a general-purpose alternative to reversed-phase (RPC), fractionating peptides by differences in charge rather than polarity. It used for multidimensional HPLC of peptide mixtures, such as tryptic digests in proteomics analyses (including iTRAQ® and ICAT®* reaction products), isolation of peptides from natural products, QC and purification of synthetic peptides, selective isolation of disulfide-linked peptides, phosphopeptides and C-terminal fragments from tryptic digests, and mapping of peptide digests (tryptic, V8, CNBr, etc.).more...